Receiver determination error

My scenarion is RFC->XI->RFC based communication. I have a RFC program which is sending the request from R/3 to the destination system(Non SAP system).

I am using the SAP XI3.0 SP12. I am testing the configuration in the Integration Directory(ID) using the "Test Configuration" functionality in 'Tools' menu of ID.I am getting an error at step 2: Received Determination. Here is the error I see:

Internal Error java.io.IOException

My scenario is RFC->XI->RFC based communication. I have a RFC program which is sending the request from R/3 to the destination system(Non SAP system).

I would appreciate your comments and suggested remedies for the error situation.

Thanks,

Raghu