Best VS2010/SAP integration strategy for a new website

Hello.

The firm I work for, an IT company, is preparing the draft for the project of a new website that should interact both with existing SAP IS-U and SAP CRM.

We have never worked with SAP, so I apologize if my question will look banal to you.

Which is in your opinion the best strategy of integration in the following scenario:

- Whole new website developed in ASP.NET C# with VS2010 Enterprise

- Existing SAP IS-U (ECC 6.0 version) and SAP CRM

- Web site hosted in a third party server farm, SAP hosted in our customer's office

In particular I would like to ask you wich are the components our customer should add to his existing SAP installation, in order to make the integration with the web possible.

I thank you in advance for any help. Regards.

Newcomsas