I noticed that the order entry screens for VA01 slightly differ between our 1511 and 1610 on-premise sandbox systems. To be more precise, I can see some differences in SAPMV45A, screen 4900 and SAPLV69A, screen 6201.
SAPMV45A, screen 4900
1511:
1610:
SAPLV69A, screen 6201
1511:
1610:
The only change, which might have something to do with changed screens in VA01 for 1610, is the fast entry of characteristic values in sales document, but I find it very unlikely.
Would somebody please post a screenshot with the attributes for SUBSCREEN_BUTTONS for SAPMV45A, screen 4900 for S/4HANA 1610? This is not exactly an issue at present, I can still create orders, I am simply trying to figure out whether this is normal.