RFC error while adding an remote monitoring entry to CEN

Hi,

I am trying to add an remote system to CEN by RZ21 i.e.

in RZ21 -> Technical Infrastructure -> Configure Central system -> Create Remote Monitoring Entry

But while testing RFC connections before saving, it giving following erros :

SC4_RZ20_COLLECT_195119Error when opening an RFC connection

Error during remote call of SAL_MS_GET_LOCAL_MS_INFO function: Error when opening an RFC connection

Error during remote call of SALC function: Error when opening an RFC connection

Error during remote call of RFC1 function: Error when opening an RFC connection

Are these errors of any concern?

or shall i go ahead and save the entries?

Please suggest.