Hi Andreas,
Pls make sure that SAP profiles which u have modified is not of the CPIC users. This is because, in both the J2EE visual admin and ABAP stack you will be having these users in the UME and will be used for communication between both the engines - ABAP & J2EE. Just make sure that all these CPIC users are having the necessary profiles/roles attached and make sure that in the Visual Admin also, all these profiles are in sync.
Cheers
_JK
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