Getting problem when loading metadata in Quality System

Hi Experts,

In our project there was an upgrade of R/3 system from 4.6 to ECC 6.0 version.

During the upgrade process I tried to delete and re-import the meta-data again in the Quality system

but it is giving the error saying no RFC destination is defined for the port SAPQS2 but we are maintaing an RFC destination for that port with the name QS2CLNT100.

Also please find below the error log we seen in the t-code sm22 in PI's Quality system.

Transaction canceled IDOC_Adaper 601 (SAP QS2 100).

Can any please let me know what to do now.

Thanks and Regards,

Pruthvi