Extended Classic PO Replication Issue

We currently use the extended classic scenario for SRM 4.0 and ECC 5.0. After a recent system refresh purchase orders currently no longer replicate to the ECC system in our Q system. I've confirmed that the RFC destinations are set up as well as material groups and HR data replicated fine. Any help and ideas as to why POs are not replicating would be helpful.

PO changes are also not replicating from SRM to ECC.