Simultaneous Clients in Solman Possible or not?

Hi Gurus

Is it possible to have 2 clients simultaneously function in solution manager.

We are already having one client configured and functioning in Solution Manager.

We would like to have another fresh client, which will be configured again and will be used after everything is set. Is this scenario possible? could any one list the possible issues , which we may face during this process.

Thanks a lot in advance.