Content Management Server-Read/Write Access

If one is migrating to a stand alone Content Management Server, then how does one control the read/write access to this CMS for the employees of an organisation?

Previously, the CMS was SAP Portal Based and hence the read/write access was controlled from the KM Content in the Portal.

Is there anything else to be kept in mind as pointers when migrating to a stand alone CMS?

Any suggestions/ideas would be greatly helpful.

Thanks

Tania