Quite interesting and theoretically this is possible too if you are planning to make use of commentary feature to write back to the database table though there is no out of box feature to achieve this directly. I would love to try this if time permits.
You process will be something like below.
Configure the Commentary feature and make sure your users are provisioned to add comments to the WebI document.
Make sure the comments that you are adding in comment section is properly updated in commentary table
Create an external procedure that looks for an entry from commentary table and understands the target table& columns to be updated, condition to be met for update and finally approval any (Not everyone should be allowed to update)
Run the external procedure that reads your commentary database and update your target table.
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