JCo creation for multiple backend systems

Hi Experts,

I have an application in which i am using two different backend systems. I have used three RFCs in my application, in which two RFCs are referring same backend system while 3rd RFC is pointing to another backend system .

Now my doubt is, Is it possible to use a single JCo connection for this application ...?

OR if i use 2 or 3 JCos then which one will give better performance...?

Thanks in advance,

JP