RFC connection

HI Gurus,

I have 2 internal hard discs in one PC.Primary hard disc(host) having win 2003 server and one SAP system , 2nd hard disc having(VMWARE machine)win 2003 server and another SAP systems. I want to connect both the SAP systems through RFC.HOw to connect these 2 machines?What are all the Steps needs to be done to connect these 2 machines and 2 SAP systems? how to ensure that the connection has establised?