CR 2016 and Microsoft Visual C++ 2005 Redistributable ?

I have some users with Xi and 2008 versions upgraded to CR 2016 and full installs of 2016 and they still rely on Microsoft Visual C++ 2005 Redistributable. How to get it working with 2010 , 2012 etc. Multiple questions: do I need to do anything on the upgraded pc's from older versions, I.e.. uninstall the older version or update that versions service packs or just update the 2016cr to the newest SP which I think is 5. I'm currently running CR 2016 SP2. If so can I just install SP5 or do I have to install in stages from 3,4 and then install 5?