Microsoft Framework Update (KB4054981) Causing Issues with Crystal Reports 13 Not Displaying

Per the title, I am having issues getting multiple Crystal Reports to display on my server-supported website. Here are the details:

• Microsoft security and quality update for framework 4.6/4.7 was applied to a server (Microsoft Server 2008 R2) the night before last and again this morning. We know that this is the culprit because once the update was rolled back, with no other solutions applied to the server, the website was displaying the Crystal Reports correctly.
• Team verified that the aspnet_client/system_web version folder that the server was looking for was present in the website directory and had the necessary files within. Also checked user computers to see if their computers were looking for similar version files.
• Team restarted IIS and verified that necessary permissions were granted for users to the Crystal Report files.
• Team was receiving the "bobj is undefined" error when locally debugging until the specific aspnet_client/system_web version folder was added to the solution (had previously worked without this version folder included).
• Team was receiving errors surrounding the crv.js and style.css files not being found until the specific aspnet_client/system_web version folder was added to the solution.
• Team has tried to add specific <SectionGroup> and <Section> code for Crystal Reports in the webconfig file as detailed by other support questions relating to the bobj error--none of which worked.

Can anyone tell me why this particular Microsoft update interferes with Crystal Reports 13? Is there a way to install these updates and have the Crystal Reports working as intended? Unfortunately, blocking these updates is not an option.