Personally I would never install any AV software on a database server. The AV software hooks up to the I/O layer and slows down the system, even if you exclude the database files from being scanned.
On an application server there's not much I/O done so it may make sense to install it there.
Markus
I have anti-virus (E-Trust - real time monitor) running on my SAP servers. However, my anti-virus application allows me to put exceptions on certain drives to prevent any additional I/O consumptions.
Never had experience w/ McAfee and SAP, sorry.
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