System Lock error

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Dear All

We are using SAP ECC 5.0 in which we have one separate Database instance Server and one Central Instance Server and 4 Dialog instance Server. We are getting the error "System lock error - Notify the Adminstrator". When i check the System log i found these errror messages :

GEH Enqueue: Transfer error while reading lock entries

GZZ > Destination: VRP_CI_VRP_65

GZZ > ENQUE_READ exception code: 8

GZZ >

R49 Communication error, CPIC return code 017, SAP return code 672

R5A > Conversation ID: 81910577

R64 > CPI-C function: CMRCV

So, i got to know that when other application server is unable to establish RFC with Central instance then this error is generated as enqueue process is on Central instance. I have checked the parameter gw/max_conn and gw/max_sys. Both are having maximum values.

Please suggest me what to do.

Regards

Shashank Shekhar.