SENDER RFC CHANNEL

hi all

i am doing rfc to rfc scenario,while executing the RFC it showing me runtime error " sender aggrement not found ": lookup of binding via CPA-cache failed.

i had maintain all the seeting like

1.i had created rfc destination in r3 system,program id inside it,gateway host,gateway service,....and i maintain same program id in sender communication channel.

while executing the rfc there is one option RFC Target system...i am giving the name of rfc destination that i have created.

but still i am getting the same error.