Unable to open the Integreation Builder

Hi All

When i try to open the IB it is giving me following message....

Error: Unable to load resource: http://ITMISAPXI:50000/rep/repository/aii_ibrep_client.jar and it aborts......

Infact, JWS is present, IB was working fine now all of a sudden it is giving this error...

i tried deleting all the Jar files from the Loal machine and also reinstalled the JWS...still same error.....