Is Adobe Reader installed?
When are you getting that error message?
Try fiddler, it likely can't find a resource or have permission to a folder or resource.
Don
OK, what is the runtime ( SDK ) you installed a what version is it?
Use SP 20 for updated CR for VS runtime which you can get from here:
https://wiki.scn.sap.com/wiki/display/BOBJ/Crystal+Reports%2C+Developer+for+Visual+Studio+Downloads
Older versions may not support 2012 R2 Server.
Don
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