Integrate HR org structure and CUA?

We are considering a new design for our authorization management on our production ECC 6.0 system.

There will be 2 productive ECC 6.0 systems; which system you use will depend on your global location. We currently utilize the HR org structure to assist us with provisioning and deprovisioning accounts on our durrent single ECC 6.0 instance, and we hang composite roles off of positions in the org structure, so that a fair amount of authorization management is automated.

If we were to put a CUA client over the two productive ECC 6.0 clients, how might that be integrated with the HR organizational model? Does CUA integrate well with an org structure? Any experiences with this would be helpful.