ICM_HTTP_CONNECTION_FAILED error in file to proxy??

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Hi

In my file to proxy,

i am maintaining one Http RFC destination..intest Connection i am getting 500 as status.

two TCP/IP destinations LCRSAPRFC and SAPSLDAPI.

i am maintaing values in SPROXSET table.

in SLDAPICUST also.

and in SXMB_ADM i configuerd Integration engine.

but i am getting error in sxmb_moni

SAP:P4></![CDATA[> 
  <SAP:AdditionalText><html><head><title>SAP Web Application Server Error</title> <style type="text/css"> body { font-family: arial, sans-serif;} </style> </head> <BODY text="#172972" link="#808080" vlink="#808080" alink="#8e236b" bgcolor=white leftmargin="0" topmargin="0" marginheight="0" marginwidth="0"> <table height="61" width="100%" border="0" cellspacing="0" cellpadding="0"><tr><td background="http://dcexi0605.aaaa.com:8030/sap/public/icman/img/bluebar_tile.gif" height="30"><table> <tr> <td width=5></td> <td width=20% nowrap><font face=arial size="-1" color=white>SAP Web Application Server </font></td><td width=75% align="right" nowrap><font face=arial size="-1" color="white"><a href="http://help.sap.com/">Help </font></td><td width=5% nowrap></font></td> </tr></table> </td><td rowspan=2 width=122 height=61 valign=top><img src= "http://dcexi0605.aaaa.com:8030/sap/public/icman/img/theme.jpg" width=122 height=61 border=0 alt="SAP"></td> </tr><tr><td background="http://dcexi0605.aaaa.com:8030/sap/public/icman/img/graybar_tile.jpg" height="31">  </td></tr> </table> <br><br> <table width=800> <tr><td width=50 nowrap> </td><td> <H2><b>404 Resource not found</b></H2><br><hr><br>Partner not reached<br><br><hr> <table border="0"> <tr><td>Error:</td><td>-20</td></tr> <tr><td>Version:</td><td>6040</td></tr> <tr><td>Component:</td><td>ICM</td></tr> <tr><td>Date/Time:</td><td>Wed Feb 28 12:28:10 2007 </td></tr> <tr><td>Module:</td><td>icxxconn_mt.c</td></tr> <tr><td>Line:</td><td>2121</td></tr> <tr><td>Server:</td><td>ciBGX30_BGX_30</td></tr> <tr><td>Detail:</td><td>Connection request from (42/31087/0) to host: dcesssss08.aaaa.biz, service: 8010 failed (NIECONN_REFUSED) AP-T42, U31087, 100 SOA_AAA, M2B-36-D-1787, 12:28:10, M0, W2, , 1/0</td></tr> </table> <p></p> </td></tr></table> <table><tr><td width=50 nowrap></td> <td nowrap><FONT SIZE=-1><a href="http://www.sap.com/">© 2001-2005, SAP AG</a></FONT></td></tr></table></SAP:AdditionalText> 
  <SAP:ApplicationFaultMessage namespace=""></SAP:ApplicationFaultMessage> 
  <SAP:Stack><b>Error when receiving by HTTP (error code: 400, error text: ICM_HTTP_CONNECTION_FAILED)</b></SAP:Stack> 
  <SAP:Retry>A</SAP:Retry> 
  </SAP:Error>

please guide me where i did mistake

regards

Ram