RFC_ERROR_COMMUNICATION: Connect from SAP gateway to RFC server failed

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while i am running my application in web browser i am getting the following error

Nov 8, 2006 12:25:39 PM SAPEngine_Application_Thread[impl:3]_36 Warn... bccom.sapmarkets.isa.catalog.webcatalog.WebCatInfo [(ilggladev04_C4D_00)ID1638024050DB11189494957156400136End|catalog.exception.backend] Error in backend catalog

1816 com.sapmarkets.isa.catalog.boi.CatalogException: com.sap.mw.jco.JCO$Exception: (102) RFC_ERROR_COMMUNICATION: Connect from SAP gateway to RFC server failed

1817 Connect_PM TYPE=R GWHOST=ilggladev04 GWSERV=sapgw47 PROGID=TREXRfcServer_48 PCS=1

1818

1819 LOCATION SAP-Gateway on host ilggladev04 / sapgw47

1820 ERROR program TREXRfcServer_48 not registered

1821

1822 TIME Wed Nov 08 12:25:39 2006

1823 RELEASE 640

1824 COMPONENT SAP-Gateway

1825 VERSION 2

1826 RC 679

1827 MODULE gwr3cpic.c

1828 LINE 1621

1829 DETAIL TP TREXRfcServer_48 not registered

1830 COUNTER 4