Integration Process not fired!

Hey all,

I have a scenario of using BPM from a file sender and inbound into R/3. I set up the Integration Process and imported into the directory. But when I run a sample message, XI never picks up the integration process and spits out an error that a receiver wasn’t determined. But actually 2 sets of receiver , 1 for file sender to Integration process and the second from Integration Process to the receiver have been set up with proper sender and receiver agreements. What could be the issue?

-Teresa