RFC Exception : Opening connection to backend failed. No data received from partner side

Hi,

This is the issue of SCPI synchronous Interface HTTPS(Sender) to RFC(SAP ECC - Receiver). The cloud connector is used to connect backend SAP ECC. The Interface is running in the PROD environment with high volume and only a few messages got failed with the below error.

Please help me to understand and rectify the issue.

Thanks and Regards,

Neeraj