Changing Receipients in Publication

Folks,

I already have a running Publication in Production env (BO 4.1 SP 3 env)

It already has a list in To field and some in Cc field.

Existing one has To :A,B,C and Cc : D,E

New one would be To : E and Cc : D

Now I changed the To as well as Cc list members.New set of values is not being picked up by the current publication.

Do I need to Unsubscribe first the publication and then scbriscibe it with changes so that the changed one would be reflected in prod.

Appreciate your inputs in changing the parameters.

BR