I have some integration scenarios where my ERP System exchanges messages with PI through RFC Sender Channel. The problem is that sometimes my RFC destinations (transaction SM59 of my ERP System) stop working. Sometimes they do not stop working but when I test them (with "Test Connection" button) the response time is VERY high! Well in both situations I have to restart my communcation channels (stop/start channel in RWB). Do you have any idea of what could be the cause of this problem? I found some wikis on SCN where people say that destinations stop working because of network problems/issues. But I am not sure that this is the cause because I have two ERP and two different PI Productive Systems and the problem always happens with one of them.