Error in upgrade phase MAIN_TRANSEXEC/STARTSAP_TRXPRA

We are working in a upgrade of EHP 5 to SP 10 of a ERP in 6.0 in the phase MAIN_TRANSEXEC/STARTSAP_TRXPRA with the text 'sapcontrol exited 2 System start Failed" we find in the log file dev_ms "No respond for client C1"